Package: MixTwice
Type: Package
Title: Large-Scale Hypothesis Testing by Variance Mixing
Version: 2.0
Imports: alabama, ashr, fdrtool, Iso, stats
Date: 2022-02-28
Author: Zihao Zheng and Michael A.Newton
Maintainer: Zihao Zheng <zihao.zheng@wisc.edu>
Description: Implements large-scale hypothesis testing by variance
        mixing. It takes two statistics per testing unit -- an
        estimated effect and its associated squared standard error --
        and fits a nonparametric, shape-constrained mixture separately
        on two latent parameters. It reports local false discovery
        rates (lfdr) and local false sign rates (lfsr). Manuscript
        describing algorithm of MixTwice: Zheng et al(2021) <doi:
        10.1093/bioinformatics/btab162>.
License: GPL-2
NeedsCompilation: no
Packaged: 2026-10-10 13:10:49 UTC; root
Depends: R (>= 3.5.0)
Repository: https://zzheng68.r-universe.dev
Date/Publication: 2022-03-02 15:50:02 UTC
RemoteUrl: https://github.com/cran/MixTwice
RemoteRef: HEAD
RemoteSha: f31a2993c756c1f83e32b0c303033bccdb37b880